Lori Anne Allison
When Johnny Depp was 20 years old, he married Lori Anne Allison and the two moved to Los Angeles, where Allison introduced Depp to Nicolas Cage, which helped secure his first acting role. Though their marriage only lasted 2 years, they remained friends and Allison refers to Depp as a “soft person” who never laid a hand on her.
Sherilyn Fenn
Depp and Sherilyn Fenn met in 1985 while filming the short film "Dummies," and dated for almost three years. Fenn has continued to speak fondly of him and voice her support for him in his legal struggle with Amber Heard by stating on Instagram, "#istandwithjohnny then & now & forever."
Jennifer Grey
Depp briefly dated Jennifer Grey in 1987, and according to Grey, Depp proposed to her two weeks after meeting her. Grey wrote on why she called off the engagement in her memoir "Out of the Corner," stating he was "crazy jealous and paranoid about what I'd been up to while he was gone."
Winona Ryder
Winona Ryder and Depp were the "it couple" of the 1990s, meeting in 1989 at Ryder's premiere for "Great Balls of Fire" and becoming engaged only five months later. However, by 1993, the couple had called it quits, with Ryder later referring to her breakup with Depp as her "first heartbreak."
Juliette Lewis
In 1993, rumors surfaced that Depp and Juliette Lewis had a brief romance after meeting on the set of "What's Eating Gilbert Grape." However, Lewis cleared the air in 2014, claiming that they never genuinely dated, and that Depp was still reeling from his breakup with Winona Ryder at the time.